Computations were performed with R 3.5.1, using Bayesian integration for HR uncertainty. Those younger than age 50 years were modeled as either taking postoperative estrogen or not those 50 and older were modeled as not receiving estrogen. A Markov model from reported HRs predicted the proportion of the population staying alive to age 80 years by 1-year and 5-year age groups at time of surgery, from age 45 to 55 years. Base mortality rates were derived from national vital statistics data. We performed a literature review that assessed hazard ratios (HRs) for mortality by disease, age, hysterectomy with or without BSO, and estrogen therapy use. To perform an updated Markov modeling to assess the optimal age for bilateral salpingo-oophorectomy (BSO) at the time of hysterectomy for benign indication. The work cannot be changed in any way or used commercially without permission from the journal.
Finding full text endnote uw madison license#
This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. Peer reviews and author correspondence are available at.
Presented at the Society for Academic Specialists in General Obstetrics and Gynecology Annual Meeting, held virtually, October 2020, with the posters being made available August 15, 2020–Augand at the inaugural Heartland Association for Gynecologic Oncology Meeting, held virtually, September 10–11, 2020.įinancial Disclosure The authors did not report any potential conflicts of interest.Įach author has confirmed compliance with the journal's requirements for authorship. Rush, MD, Division of Gynecology Oncology, Department of Obstetrics and Gynecology, UW Health Hospital and Clinics, Madison, WI email. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, UW Health Hospital and Clinics, and the Department of Statistics and the Department of Biostatistics & Medical Informatics, University of Wisconsin–Madison, Madison, Wisconsin.Ĭorresponding author: Shannon K.
0 kommentar(er)
